Intermediate Organic Chemistry - Part 2

Jeffrey S. Moore, Michael Evans and Nicholas M. Llewellyn, University of Illinois at Urbana-Champaign

Organic chemistry course covering intermediate topics in structure and reactivity with special applications to the life sciences.

This course covers topics on the structure and reactivity of organic compounds with an emphasis on bioorganic chemistry and applications to life sciences.  Stereochemical concepts and aspects of non-covalent interactions relevant to enzyme-catalyzed reactions are presented.  The mechanistic approach of this course is designed to help students build intuition about how bioorganic compounds undergo their chemical transformations. The structure and reactivity of the major classes of bioorganic molecules - proteins, carbohydrates, and nucleic acids - will be covered in detail. An introduction to biosynthesis will be presented, along with the use of contemporary literature and structural databases. Throughout the course, emphasis will be placed on mechanism-based problem-solving skills to help students understand and think critically about the organic chemistry of living systems. This course, orgchem2b, and its prerequisite, orgchem2a, are equivalent to a second-semester organic chemistry course; these courses are well suited for students in agricultural, nutritional and biological sciences, as well as premedical, predental, and preveterinary programs.

Syllabus

Lesson

Topic

1

Topic Relationships

2

Prochirality

3

Amino Acids

4

3D Protein Structure & Noncovalent Interactions

5

Peptide Chemistry

6

Enzyme Catalysis

7

Enzyme Mechanisms

8

Enzyme Inhibition

9

Enzyme Stereochem.

10

Enzymatic Elimin.

11

Biosynthesis

12

Exam Review

13

Monosaccharides

14

Carbohydrate Reactions

15

Oligosaccharides

16

Nucleic Acids

17

Bioorganic Phosphorus

18

Protein Biosynthesis

19

Literature & Databases

20

Exam Review

Recommended Background

One semester of organic chemistry and orgchem2a.

Course Format

Content is delivered via 5-minute videos we call webcasts. Webcasts of a related theme, along with a set of PDF lecture notes, constitute a lesson. There are 20 lessons in the course. Students are expected to watch and study these materials independently, much as they would study a traditional textbook. We encourage students to comment with feedback or questions via the discussion board. 

Bundled with each lesson are problems designed to help students test their understanding of webcast material and apply their knowledge to new situations. All problems in the course are delivered to students electronically and machine graded with real-time feedback. Problems of the Day are covered by instructors during class time and emphasize the acquisition of skills, strategies, and attitudes for heuristic (non-algorithmic) problem solving. Pressure Point Problems, or "P3s," are more difficult, timed problems that help students prepare for exam situations. Because training effective problem solvers is one of our primary goals, we strongly emphasize tackling and understanding the problems associated with each lesson. 

Placing lecture contents online has allowed us to use class time almost exclusively to sharpen students' problem solving abilities. During discussion sessions, students and instructors communicate online through web-based conferencing technology. Using this technology, we are able to run discussion sessions for large numbers of students while maintaining an interactive, engaging learning environment. In all discussion sessions, the emphasis is on student activity and participation.

FAQ

  • Will I get a certificate for this course?

    Yes. Students who successfully complete the class will receive a certificate signed by the instructor.

Dates:
  • Date to be announced, 7 weeks
Course properties:
  • Free:
  • Paid:
  • Certificate:
  • MOOC:
  • Video:
  • Audio:
  • Email-course:
  • Language: English Gb

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